Which is NOT a pathophysiologic factor of acne?

Which is NOT a pathophysiologic factor of acne?

• A. Comedogenesis
• B. Production of excessive sebum
• C. Alteration in follicular growth
• D. Dairy consumption

Answer: (D)

Acne lesions arise from processes inside the skin: increased sebum production stimulated by androgens, abnormal keratinocyte turnover causing follicular plugging (comedo formation), and bacterial growth with inflammation in the pilosebaceous unit. Comedogenesis specifically refers to the clogging that starts these lesions, while excess sebum provides the oily environment, and altered follicular growth leads to plugging. Dairy consumption, while it may influence hormones and inflammation in some individuals, is not a direct skin pathophysiologic mechanism that creates acne lesions. It acts more as an external modulator rather than part of the fundamental pilosebaceous changes that produce acne.

Acne lesions arise from processes inside the skin: increased sebum production stimulated by androgens, abnormal keratinocyte turnover causing follicular plugging (comedo formation), and bacterial growth with inflammation in the pilosebaceous unit. Comedogenesis specifically refers to the clogging that starts these lesions, while excess sebum provides the oily environment, and altered follicular growth leads to plugging. Dairy consumption, while it may influence hormones and inflammation in some individuals, is not a direct skin pathophysiologic mechanism that creates acne lesions. It acts more as an external modulator rather than part of the fundamental pilosebaceous changes that produce acne.